ABOUT
AMALIAN

All AMALIAN hyaluronic acid fillers are exclusively made of ultra-pure, protein-free hyaluronic acid, which is totally free from animal components.

As CE-certified medical devices, all AMALIAN hyaluronic acid fillers meet the highest German and international quality require-ments and ensure absolute sterility as well as non-cyctotoxic and biologically safe products. This ensures safety for your individual treatment program.

The AMALIAN product range is designed to help you:

  • Restore volume lost to aging for a youthful look
  • Enhance shape and definition for a balanced skin
  • Refresh and improve the general condition of your skin for a radiant and hydrated look
  • Treat specific facial areas such as cheeks, mouth/nose folds, lips

With AMALIAN you benefit from all the advantages of a premium hyaluronic acid treatment:

  • Fully degradable
  • No undesired long-term effects
  • Excellent biocompatibility, clinically proven
  • No allergy test required

Clinical Evidence

Clinical data of over 900 patients treated with all the different types of the AMALIAN dermal implants reveal that the products with all its types are clinically safe and significantly effective in the correction of volume losses or defects related to disease or age in facial skin in its intended use. Post-market-follow-up studies have confirmed these positive results. All final products bear the same material composition, stem from the same raw material and differ mainly in HA concentrations.

For AMALIAN SF line there is a proven record of clinical data from over 200 treatments which have shown significant effectiveness and excellent long-term safety for all products of the AMALIAN SF line.

On a five-point scale, the degree of improvement from the baseline value was recorded directly after treatment, 2-3 weeks after treatment as well as 3, 6 and 12 months after treatment. Improvement by at least 1 scale point was maintained for 6 months, whereby even after 12 months, the base line value did not return.

Treatment with the AMALIAN SF 24 advanced showed significant improvement compared to baseline even after 9 months (P value < 0.00001). All AMALIAN SF products resulted in treatments with responder rates of at least 75% at month 6-7.

Excellent safety of each AMALIAN SF product was evident as no product related or severe adverse reactions occurred. There were no lumps, inflammations, nodules or late on-set reactions. Only mild to moderate injection related, short-term side-effects with a mean duration of less than 3 days occurred.

Patient and physician satisfaction were monitored using the Global Aesthetics Scale (GAIS) on a scale of -1 to 3. Directly after treatment, both patients and physicians reported the appearance of area treated as highly to very highly improved: 2.52 and 2.46, respectively.